Clinical uses of Calcium Phosphate Cements.

Clinical uses of Calcium Phosphate Cements.

The unique combination of biocompatibility, osteoconductivity and mouldability make CPCs suitable for a wide range of applications. The clinical uses cover both orthopaedics and dentistry.

The use of CPCs as a bone graft substitute has already been established. Successful clinical trials were conducted in maxillofacial reconstruction and in the treatment of the distal radius fracture. In additions, attempts have been made to use CPC for calcaneal fractures, hip fractures, the augmentation of osteoporotic vertebral bodies, tibial plateau fractures, the restoration of pedicle screw fixation, the reinforcement of thoracolumbar burst fractures, and the reinforcement of cancellous bone screws.

In dentistry, pre-clinical studies demonstrate their use in procedures like furcation perforation repair, treatment of periodontal infrabony defects, root canal filling/sealing, root apexification and alveolar ridge augmentation, and as bone filler for gaps around oral implants.